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Deamination is the
removal of an
amino group from a molecule.
Enzymes that
catalyse this
reaction are
called deaminases. In the
human body, deamination...
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Oxidative deamination is a form of
deamination that
generates α-keto
acids and
other oxidized products from amine-containing compounds, and
occurs primarily...
- it is
inherently unstable, and can
change into
uracil (spontaneous
deamination). This can lead to a
point mutation if not
repaired by the DNA repair...
- the
breakdown of fat in
adipose tissue to
fatty acids, and
oxidative deamination of
neurotransmitters by
monoamine oxidase.
There are many
signals that...
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aliphatic alpha- and beta-hydroxylation, N-oxidation, N-dealkylation, and
deamination. The
known metabolic pathways include:
Methamphetamine and amphetamine...
-
members that
encode mitochondrial enzymes which catalyze the
oxidative deamination of amines, such as norepinephrine,
serotonin and tyramine. A mutation...
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ammonolysis of 2-bromopropanoic acid.
Alanine is
broken down by
oxidative deamination, the
inverse reaction of the
reductive amination reaction described above...
- the
analogous RNA base uracil,
which has no
methyl group.
Spontaneous deamination of 5-methylcytosine
converts it to thymine. This
results in a T:G mismatch...
- high
mutation rate of
methylated CpG sites: the
spontaneously occurring deamination of a
methylated cytosine results in a thymine, and the
resulting G:T...
- APOBEC3G
belongs to the
family of
cytidine deaminases that
catalyze the
deamination of
cytidine to
uridine in the
single stranded DNA substrate. The C-terminal...
