-
Alkylation is a
chemical reaction that
entails transfer of an
alkyl group. The
alkyl group may be
transferred as an
alkyl carbocation, a free radical,...
- properties. The
other metabolites identified include a N-
dealkylated metabolite, and an O-
dealkylated 1/16
metabolite with a
plasma half-life of 59 hours....
-
methylcobalamin for use as cofactors. That is,
methylcobalamin is
first dealkylated and then regenerated.
Methylcobalamin can be
produced in the laboratory...
- compounds. JWH-018 and its N-
dealkylated metabolite were only
detected in
small amounts, with
hydroxylated N-
dealkylated metabolites comprising the primary...
- (2RNH2 → R2NH + NH3). And finally,
quaternary ammonium salts can be
dealkylated using ethanolamine: R4N+ + NH2CH2CH2OH → R3N + RN+H2CH2CH2OH Aminonaphthalenes...
-
ethers (as well as
activated primary alkyl ethers), on the
other hand are
dealkylated through a
bimolecular mechanism involving two BBr3-ether adducts. RO+(− BBr3)CH3 +...
- for half an hour to
three hours.
Lidocaine is
about 95%
metabolized (
dealkylated) in the
liver mainly by CYP3A4 to the
pharmacologically active metabolites...
-
chemical compounds. They can be used to form
protecting groups and as N-
dealkylating agents. They are
listed as
extremely hazardous substances. 'A new reagent...
-
alkylated with
propylene to give
isomers of cymene,
which can be
oxidatively dealkylated analogous to the ****ene process.
Another method,
involves carbonylation...
- 24 nM at δ and 72 nM at μ.
However once
inside the body, RWJ-394674 is
dealkylated to its
monodesethyl metabolite RWJ-413216,
which is a
potent agonist...
