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Histone deacetylases (EC 3.5.1.98, HDAC) are a
class of
enzymes that
remove acetyl groups (O=C-CH3) from an ε-N-acetyl
lysine amino acid on both histone...
- A
protein deacetylase is any
enzyme that
removes acetyl groups from
lysine amino acids in proteins. The main ones are
histone deacetylases (HDACs) and...
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Histone deacetylase inhibitors (HDAC inhibitors, HDACi, HDIs) are
chemical compounds that
inhibit histone deacetylases.
Since deacetylation of histones...
- In enzymology, an
acetylspermidine deacetylase (EC 3.5.1.48) is an
enzyme that
catalyzes the
chemical reaction N8-acetylspermidine + H2O ⇌ {\displaystyle...
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Histone deacetylase 6 is an
enzyme that in
humans is
encoded by the HDAC6 gene. HDAC6 has
emerged as a
highly promising candidate to
selectively inhibit...
- The
enzyme N-acetylgalactosaminoglycan
deacetylase (EC 3.1.1.58)
catalyzes the
reaction N-acetyl-D-galactosaminoglycan + H2O ⇌ {\displaystyle \rightleftharpoons...
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Histone deacetylase 1 (HDAC1) is an
enzyme that in
humans is
encoded by the HDAC1 gene.
Histone acetylation and deacetylation,
catalyzed by multisubunit...
- (Nucleosome
Remodeling Deacetylase) complex, is a
group of ****ociated
proteins with both ATP-dependent
chromatin remodeling and
histone deacetylase activities. As...
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deacetylase (EC 3.5.1.104, HP310, PgdA, SpPgdA, BC1960,
peptidoglycan deacetylase, N-acetylglucosamine
deacetylase,
peptidoglycan GlcNAc deacetylase,...
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Histone deacetylase 5 is an
enzyme that in
humans is
encoded by the HDAC5 gene.
Histones play a
critical role in
transcriptional regulation, cell cycle...
