- This
reaction is
termed deISGylation, as the
initial conjugation of ISG15 to
newly synthesized proteins is
termed ISGylation, a
process akin to ubiquitination...
-
evolutionary repurposing of
viral proteases for
deubiquitination and
deISGylation as
mechanism for
influencing the host
innate immune system response is...
- ISG15-peptide
fusions and also
removes ISG15 (
deISGylation) from
native conjugates. The
effects of
ISGylation are
incompletely understood and
involve both...
- Yuan Y,
Ritchie KJ, Kim KI,
Peterson LF,
Shuai K,
Zhang DE (February 2003). "Protein
ISGylation modulates the JAK-STAT
signaling pathway".
Genes & Development...
-
Giannakopoulos NV,
Virgin HW,
Zhang DE (2004). "Interferon-Inducible
Ubiquitin E2, Ubc8, Is a
Conjugating Enzyme for
Protein ISGylation". Mol. Cell. Biol. 24 (21):...
- Chen*, and Chen Wang. Herc5
Attenuates Influenza A
Virus by
Catalyzing ISGylation of
Viral NS1 Protein.
Journal of Immunology, 2010, 184, 5777-5790 6. Bo...
- PMIDĀ 17018293. Zou W, Wang J,
Zhang DE (2007). "Negative
Regulation of ISG15 E3
ligase EFP
through its auto
ISGylation". Biochem. Biophys. Res. Commun. 354...