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Darbepoetin alfa (INN) /dɑːrbəˈpoʊɪtɪn/ is a re-engineered form of
erythropoietin containing 5
amino acid
changes (N30, T32, V87, N88, T90) resulting...
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Essential Medicines.
Commercially available agents include epoetin alfa and
darbepoetin alfa, and biosimilars. Use
among athletes is
prohibited by the World...
- the use of erythropoiesis-stimulating
agents (ESAs) such as
epogen and
darbepoetin. The
advisory recommended caution in
using these agents in
cancer patients...
- cell culture, and
include Epogen/Procrit (epoetin alfa) and
Aranesp (
darbepoetin alfa); they are used in
treating anemia resulting from
chronic kidney...
- was
expelled from the
Games the next day,
after testing positive for
darbepoetin (a
medicine which boosts red
blood cell count; the
substance was not...
-
three skiers had
overly high red
blood cell
counts indicating the use of
darbepoetin, a drug used to
treat anemia. At the time, the drug was not specifically...
- to
epoetin for
patients receiving dialysis (the
EMERALD study), or to
darbepoetin for
patients with
chronic kidney disease who were not
receiving dialysis...
- : 3 Erythropoiesis-stimulating
agents such as
erythropoietin (EPO),
darbepoetin (dEPO), hypoxia-inducible
factor (HIF) stabilizers,
methoxy polyethylene...
- Muehlegg.
Muehlegg had won
three gold
medals but
tested positive for
darbepoetin after winning his third. He was
originally allowed to keep the other...
- has an in vivo half-life of
around 135
hours (5.6 days) as
compared to
darbepoetin alfa
which has a half life of
around 21 to 70 hours, the half life of...