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Samuel J.
Danishefsky (born
March 10, 1936) is an
American chemist working as a
professor at both
Columbia University and the
Memorial Sloan-Kettering...
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Danishefsky's diene (Kitahara diene) is an
organosilicon compound and a
diene with the
formal name trans-1-methoxy-3-trimethylsilyloxy-buta-1,3-diene...
- The
Danishefsky Taxol total synthesis in
organic chemistry is an
important third Taxol synthesis published by the
group of
Samuel Danishefsky in 1996...
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diene is 1-methoxy-3-trimethylsiloxy-buta-1,3-diene,
otherwise known as
Danishefsky's diene. It has
particular synthetic utility as
means of
furnishing α...
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activity but
simpler to produce. The
concept was
introduced by
Samuel J.
Danishefsky in 2006.
Notable examples of this
strategy are the
potential drug ixabepilone...
- Synthesis. 2008 (3): 409–412. doi:10.1055/s-2008-1032023. Lambert, T. H.;
Danishefsky, S. J. (2006). "Total
Synthesis of UCS1025A".
Journal of the American...
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tolerates the
presence of
carbamate and
ether substituents.
Samuel J.
Danishefsky's synthesis of both (+) and (-)
peribysin began with a Saegusa–Ito oxidation...
- reaction,
reacting with a wide
variety of dienes. In one example, a
Danishefsky-type
diene is
reacted with a
cyclopentenone to
yield a
fused tricyclic...
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below is an
excerpt of the
synthesis of an
analogue of
Mitomycin C by
Danishefsky. The
exchange of a
protecting group from a
methyl ether to a MOM-ether...
- doi:10.1002/14356007.a15_077. ISBN 9783527306732. Ross, A. G.; Li, X.;
Danishefsky, S. J. (2012). "Preparation of Cyclobutenone".
Organic Syntheses. 89:...