- (KiTooltip
Inhibitor constant)
Ratio Ref
MORTooltip μ-Opioid
receptor DORTooltip δ-Opioid
receptor KORTooltip κ-Opioid
receptor MOR:DOR:KOR
Morphine 1...
- (KiTooltip
Inhibitor constant)
Ratios Refs
MORTooltip μ-Opioid
receptor DORTooltip δ-Opioid
receptor KORTooltip κ-Opioid
receptor MOR:DOR:KOR
Naloxone 1...
-
receptor 59
Antagonist Human MORTooltip μ-Opioid
receptor >10,000 ND
Human DORTooltip δ-Opioid
receptor >10,000 ND
Human KORTooltip κ-Opioid
receptor >10,000...
- 120–8,300 ≥1,000 (EC50) 5.4–18.6 17 ((+)) ≥240 (EC50)
Human Rat
Human DORTooltip δ-Opioid
receptor >10,000 57,600–100,000 ≥2,900 690 (+))
Human Rat KORTooltip...
-
MORTooltip μ-Opioid
receptor 0.2157 0.081
Partial agonist Human Monkey 38%±10
DORTooltip δ-Opioid
receptor 2.9–6.1 0.82
Antagonist Human Monkey 0
KORTooltip κ-Opioid...
- Affinities,
KiTooltip Inhibitor constant Ratio MORTooltip μ-opioid
receptor DORTooltip δ-opioid
receptor KORTooltip κ-opioid
receptor MOR:DOR:KOR 0.39 nM >1...
- (KiTooltip
Inhibitor constant)
Ratio Ref
MORTooltip μ-Opioid
receptor DORTooltip δ-Opioid
receptor KORTooltip κ-Opioid
receptor MOR:DOR:KOR
Codeine 79...
-
Ratios Refs
MORTooltip μ-Opioid
receptor KORTooltip κ-Opioid
receptor DORTooltip δ-Opioid
receptor MOR:KOR:DOR 1.0 nM 3.9 nM 149 nM 1:4:149 0.0825 nM 0...
-
opioids at
opioid receptors (Ki, nM)
Compound MORTooltip mu-Opioid
receptor DORTooltip delta-Opioid
receptor KORTooltip kappa-Opioid
receptor Ref 3-HO-PCP 60...
- (KiTooltip
Inhibitor constant)
Ratio Ref.
MORTooltip μ-Opioid
receptor DORTooltip δ-Opioid
receptor KORTooltip κ-Opioid
receptor MOR:DOR:KOR
Oxycodone 18...
