- (deoxyribozyme or
DNAzyme)
catalyze a
reaction when
interacting with the
appropriate input, such as a
matching oligonucleotide.
These DNAzymes are used to build...
- Deoxyribozymes, also
called DNA enzymes,
DNAzymes, or
catalytic DNA, are DNA
oligonucleotides that are
capable of
performing a
specific chemical reaction...
-
DNAzymes is RNA-cleaving
types which have been used to
detect different metal ions and
designing therapeutic agents.
Several metal-specific
DNAzymes have...
-
DNAzymes can be
modified to
include LNA residues,
producing LNAzymes (LNA-modified
DNAzymes).
These modified oligonucleotides, like
their DNAzyme relatives...
- Deoxyribozymes, also
called DNAzymes or
catalytic DNA, are
artificial DNA-based
catalysts that were
first produced in 1994.
Almost all
DNAzymes require metal ions...
-
catalytic DNA or
DNAzymes.
Several metal-specific
DNAzymes have been
reported including the GR-5
DNAzyme (lead-specific), the CA1-3
DNAzymes (copper-specific)...
-
delivery system for
therapeutic DNAzymes.
International Journal of
Pharmaceutics 479, 150-158. Rivory, L. et al (2006) The
DNAzymes Rs6, Dz13, and DzF have potent...
-
Johnson &
Johnson Research (JJR), we were
already exploring ways to
exploit DNAzymes (deoxyribozymes) for
diagnostic applications.
These fascinating molecules...
-
aptamers can be
combined with
nucleic acid enzymes, such as RNA-cleaving
DNAzymes,
providing both
target recognition and
signal generation in a
single molecule...
-
catalytic DNA (Deoxyribozyme, also
called DNAzyme) with RNA-cleavage activity.
After only a few w****s, a
DNAzyme with
significant catalytic activity had...
