- Deoxyribozymes, also
called DNA enzymes,
DNAzymes, or
catalytic DNA, are DNA
oligonucleotides that are
capable of
performing a
specific chemical reaction...
- (deoxyribozyme or
DNAzyme)
catalyze a
reaction when
interacting with the
appropriate input, such as a
matching oligonucleotide.
These DNAzymes are used to build...
-
including the GR-5
DNAzyme (lead-specific), the CA1-3
DNAzymes (copper-specific), the 39E
DNAzyme (uranyl-specific) and the NaA43
DNAzyme (sodium-specific)...
-
macular degeneration.
Trials of Dz13 were
suspended in 2013. Dz13 is a 10-23
DNAzyme that
targets c-Jun, a
transcription factor found in
diseased blood vessels...
- metal-specific
DNAzymes have been
reported including the GR-5
DNAzyme (lead-specific), the CA1-3
DNAzymes (copper-specific), the 39E
DNAzyme (uranyl-specific)...
-
DNAzymes can be
modified to
include LNA residues,
producing LNAzymes (LNA-modified
DNAzymes).
These modified oligonucleotides, like
their DNAzyme relatives...
-
catalytic DNA or
DNAzymes.
Several metal-specific
DNAzymes have been
reported including the GR-5
DNAzyme (lead-specific), the CA1-3
DNAzymes (copper-specific)...
- made of the E6
Deoxyribozymes (or
DNAzyme)
which react to
specific oligonucleotide input. Upon reaction, the
DNAzyme cleaves the
substrate producing an...
-
catalytic DNA (Deoxyribozyme, also
called DNAzyme) with RNA-cleavage activity.
After only a few w****s, a
DNAzyme with
significant catalytic activity had...
-
aptamers can be
combined with
nucleic acid enzymes, such as RNA-cleaving
DNAzymes,
providing both
target recognition and
signal generation in a
single molecule...
