Definition of DARPins. Meaning of DARPins. Synonyms of DARPins

Here you will find one or more explanations in English for the word DARPins. Also in the bottom left of the page several parts of wikipedia pages related to the word DARPins and, of course, DARPins synonyms and on the right images related to the word DARPins.

Definition of DARPins

No result for DARPins. Showing similar results...

Meaning of DARPins from wikipedia

- for four- (N2C) or five- (N3C) repeat DARPins is rather small for a biologic (ca 10% of the size of an IgG). DARPins constitute a new class of potent, specific...
- depending on the exact design. Several mono-DARPins can be linked (genetically or chemically) to multi-DARPins, which then combine multiple activities in...
- PMID 16299519. S2CID 84757398. Stumpp MT, Binz HK, Amstutz P (August 2008). "DARPins: a new generation of protein therapeutics". Drug Discov. Today. 13 (15–16):...
- Ankyrin Repeat Proteins (DARPins) were created as a robust alternative scaffold for binding proteins (antibody mimetics). DARPins are derived from naturally...
- (roughly 19 kDa in size) by utilising a rigid imaging scaffold, and using DARPins as modular binding domains between the scaffold and the protein of interest...
- combat COVID-19, Novartis bought 6% of all shares outstanding in Swiss DARPin research company Molecular Partners AG at CHF 23 per share. In December...
- domain antibody fragments (Nanobodies), designed ankyrin repeat proteins (DARPins) and aptamers. Disease detection at the molecular level is driving the...
- as an entry inhibitor. CD4 specific Designed Ankyrin Repeat Proteins (DARPins) potently block viral entry of diverse strains and are being developed...
- Intracellular Intrabody Antibody mimetics Affibody molecule Affilin Affimer Affitin Alphabody Anticalin Avimer DARPin Kunitz domain peptide Monobody nanoCLAMP...
- Plückthun, A (August 2014). "Engineered proteins with desired specificity: DARPins, other alternative scaffolds and bispecific IgGs". Curr Opin Struct Biol...