-
Cytosine (/ˈsaɪtəˌsiːn, -ˌziːn, -ˌsɪn/) (symbol C or Cyt) is one of the four
nucleotide bases found in DNA and RNA,
along with adenine, guanine, and thymine...
- In enzymology, a
cytosine deaminase (EC 3.5.4.1) is an
enzyme that
catalyzes the
chemical reaction cytosine + H2O ⇌ {\displaystyle \rightleftharpoons }...
- prokaryotes, even
though the rate of
cytosine DNA
methylation can
differ greatly between species: 14% of
cytosines are
methylated in
Arabidopsis thaliana...
- are read as
cytosines after sequencing represent methylated cytosines,
while those that are read as
thymines represent unmethylated cytosines in the genomic...
-
Cytosine glycols are
intermediate unstable products of
cytosine oxidation. These, in turn, are
thought to
undergo deamination to
uracil glycol, dehydration...
- methyltransferases. In mammals, 70% to 80% of CpG
cytosines are methylated.
Methylating the
cytosine within a gene can
change its expression, a mechanism...
-
eukaryotes methylate only a
small percentage of
these sites, but 70-80% of CpG
cytosines are
methylated in vertebrates. In
mammalian cells,
clusters of CpG at...
- and
analyzing naturally-manifested
methylated cytosines in vivo
rather than
chemically methylated cytosines. In 1970, a
breakthrough occurred when it was...
-
methyltransferases (N-4
cytosine-specific DNA methylases) are
enzymes that
specifically methylate the
amino group at the C-4
position of
cytosines in DNA. Such enzymes...
- Cytarabine, also
known as
cytosine arabinoside (ara-C), is a
chemotherapy medication used to
treat acute myeloid leukemia (AML),
acute lymphocytic leukemia...
