- and
fluid secretion that lead to
cystogenesis are two
hallmark features in ADPKD.
During the
early stages of
cystogenesis,
cysts are
attached to
their parental...
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shown to be
activated in
tumor tissue from both
humans and mice.
Renal cystogenesis and
tumorigenesis in BHD have been
shown to be
driven by the constitutive...
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suggesting a
common mechanism underlying cystogenesis between ADPKD and ARPKD. The FPC
protein is also
found on the centrosomes...
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Gulieva RE,
Churchill AJ, Kim YK, et al. (November 2017). "Organoid
cystogenesis reveals a
critical role of
microenvironment in
human polycystic kidney...
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reveals LRP5
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canonical Wnt
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hepatic cystogenesis".
Proceedings of the
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constitutive activation, due to FLCN mutations,
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tumorigenesis in Birt–Hogg–Dubé syndrome.
Nuclear localization and...
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