-
aminopeptidase (IRAP) is a
protein that in
humans is
encoded by the
leucyl and
cystinyl aminopeptidase (LNPEP) gene. IRAP is a type II
transmembrane protein which...
-
aminopeptidase activities),
alanyl aminopeptidase (aminopeptidase M/N), leucyl/
cystinyl aminopeptidase (oxytocinase/vasopressinase), and
membrane dipeptidase (leukotriene...
-
vitamin C.
Oxytocin is
known to be
metabolized by the oxytocinase, leucyl/
cystinyl aminopeptidase.
Other oxytocinases are also
known to exist. Amastatin,...
- neuropeptide, oxytocin. The most well-characterized
oxytocinase is leucyl/
cystinyl aminopeptidase,
which is also an enkephalinase.
Other oxytocinases are...
- (NEP)
Dipeptidyl peptidase 3 (DPP3)
Carboxypeptidase A6 (CPA6) Leucyl/
cystinyl aminopeptidase (LNPEP) Angiotensin-converting
enzyme (ACE) Enkephalinase...
-
leucyl aminopeptidase (Aeromonas
proteolytica aminopeptidase), leucyl/
cystinyl aminopeptidase (oxytocinase/vasopressinase), and, to a
lesser extent, glutamyl...
-
downstream signaling cascades Nuclear membrane, ER
membrane LNPEP (Leucyl-
cystinyl aminopeptidase) Q9UIQ6
Release of an N-terminal
amino acid,
cleaves before...
-
following chemical reaction Hydrolysis of
dipeptides (e.g.,
leukotriene D4,
cystinyl-bis-glycine, some β-lactam
antibiotics (e.g., carbapenem)) This membrane-bound...
-
including leukotriene D4, the beta-lactam ring of some antibiotics, and
cystinyl-bis-glycine (cys-bis-gly)
formed during glutathione degradation. GRCh38:...
-
aminopeptidase EC 3.4.11.2:
membrane alanyl aminopeptidase EC 3.4.11.3:
cystinyl aminopeptidase EC 3.4.11.4:
tripeptide aminopeptidase EC 3.4.11.5: prolyl...
