- settings, is the
cynomolgus monkey which derives from Gr****
Kynamolgoi meaning "dog milkers". It has also been
suggested that
cynomolgus refers to a race...
- (46%), and
elevated total blood bilirubin (27%). In
gonadally intact male
cynomolgus monkeys,
vosilasarm suppressed testosterone levels by
around 50% (from...
- No
teratogenicity has been
observed in
doses up to 2000 mg/kg/day in
cynomolgus monkeys,
representing an
equivalent 20x
exposure of the
maximum recommended...
- for
important antibody isotypes and
subtypes include rhesus macaques,
cynomolgus monkeys, and baboons. Therefore,
certain antibodies will only
react with...
-
investigated by the Mayo Clinic.
Preclinical toxicology studies of PRC200-SS in
cynomolgus monkeys showed dose
proportional kidney toxicity,
precluding any further...
-
primates (including the
African chimpanzee, the
sooty mangabey, and the
cynomolgus macaque), armadillos, and red squirrels.
Multilocus sequence typing of...
- fur
farms also
appear to
require dietary taurine. The rhesus,
cebus and
cynomolgus monkeys each
require taurine at
least in infancy. The
giant anteater also...
-
generation of
lipid peroxidation products in
erythrocytes and
plasma of male
cynomolgus macaques".
Journal of
Clinical Biochemistry and Nutrition. 64 (2): 129–142...
- 1964. The
center uses five
types of non-human
primates in its research:
cynomolgus macaques,
African green monkeys, mangabeys, pig-tailed
macaques and rhesus...
-
bioavailability was
found to be
excellent in dogs, good in mice, but
modest in
cynomolgus non-human primates.
Prediction of
human oral
bioavailability from pre-clinical...