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Cyclophilins (CYPs) are a
family of
proteins named after their ability to bind to
ciclosporin (cyclosporin A), an
immunosuppressant which is
usually used...
-
Peptidylprolyl isomerase A (PPIA), also
known as
cyclophilin A (CypA) or
rotamase A is an
enzyme that in
humans is
encoded by the PPIA gene on chromosome...
-
proteins that have
prolyl isomerase activity and are
related to the
cyclophilins in function,
though not in
amino acid sequence.
FKBPs have been identified...
- the
function of lymphocytes. It does this by
forming a
complex with
cyclophilin to
block the
phosphatase activity of calcineurin,
which in turn decreases...
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Peptidylprolyl isomerase D (
cyclophilin D), also
known as PPID, is an
enzyme which in
humans is
encoded by the PPID gene on
chromosome 4. As a member...
- as in a few archaebacteria, and thus are
highly conserved. Like
other cyclophilins, PPIB
forms a β-barrel
structure with a
hydrophobic core. This β-barrel...
- alpha-3
country code for
Cyprus CYP, ISO 4217 code for the
Cypriot pound Cyclophilin Cytochrome P450,
isoenzyme Cypripedium,
orchid genus This disambiguation...
-
identified two
conserved signature indels (CSIs) in
their proteins:
cyclophilin-like
protein and
inner mitochondrial membrane protease ATP23,
which are...
- conditions, such as
ischemic reperfusion injury, AIDS, and cancer. Like
other cyclophilins, PPIC
forms a β-barrel
structure with a
hydrophobic core. This β-barrel...
-
HUMAN CALCINEURIN HETERODIMER 1m63:
Crystal structure of calcineurin-
cyclophilin-cyclosporin
shows common but
distinct recognition of immunophilin-drug...
