Definition of Cycloguanil. Meaning of Cycloguanil. Synonyms of Cycloguanil

Here you will find one or more explanations in English for the word Cycloguanil. Also in the bottom left of the page several parts of wikipedia pages related to the word Cycloguanil and, of course, Cycloguanil synonyms and on the right images related to the word Cycloguanil.

Definition of Cycloguanil

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Meaning of Cycloguanil from wikipedia

- Cycloguanil is a dihydrofolate reductase inhibitor, and is a metabolite of the antimalarial drug proguanil; its formation in vivo has been thought to...
- breastfeeding. Proguanil is converted by the liver to its active metabolite, cycloguanil. It is on the World Health Organization's List of Essential Medicines...
- Buformin Chlorazanil Chlorproguanil Clociguanil Cloguanamil Cloquanamil Cycloguanil Dametralast Diallylmelamine (DAM) Guanazole Irsogladine Metformin Methylphenobarbital...
- essential to pyrimidine biosynthesis. Proguanil, via its metabolite cycloguanil, functions as a dihydrofolate reductase inhibitor, halting parasitic...
- dihydrofolate reductase. Examples include:[citation needed] Proguanil (>cycloguanil) Chlorproguanil The disinfectants chlorhexidine, polyaminopropyl biguanide...
- DHFR inhibitors pyrimethamine cycloguanil biguanides chlorproguanil proguanil# Sulfonamides sulfadoxine sulfalene Co-formulation sulfadoxine/pyrimethamine...
- DHFR inhibitors pyrimethamine cycloguanil biguanides chlorproguanil proguanil# Sulfonamides sulfadoxine sulfalene Co-formulation sulfadoxine/pyrimethamine...
- compounds in water. Pharmaceutical drugs formulated this way include cycloguanil pamoate, hydroxyzine pamoate, imipramine pamoate, olanzapine pamoate...
- JPC-2056 Oral piritrexim, a treatment for metastatic urothelial cancer. Cycloguanil, a metabolite of proguanil (a component of the oral antimalarial atovaquone-proguanil...
- but primarily is mediated through conversion to the active metabolite cycloguanil. This inhibits the malarial dihydrofolate reductase enzyme. Its most...