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Cyclins are
proteins that
control the
progression of a cell
through the cell
cycle by
activating cyclin-dependent
kinases (CDK).
Cyclins were originally...
- (July 1995). "Mechanism of CDK
activation revealed by the
structure of a
cyclinA-CDK2 complex". Nature. 376 (6538): 313–20. Bibcode:1995Natur.376..313J...
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Cyclin-dependent
kinases (CDKs) are a
predominant group of serine/threonine
protein kinases involved in the
regulation of the cell
cycle and its progression...
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Cyclina sinensis,
commonly known as
Chinese venus,
black clam, iron clam, and
Korean cyclina clam, is a clam
species in the
venus clam family, Veneridae...
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Cyclin D is a
member of the
cyclin protein family that is
involved in
regulating cell
cycle progression. The
synthesis of
cyclin D is
initiated during...
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levels of
cyclin D increase. In
response to this trigger,
cyclin D
binds to
existing CDK4/6,
forming the
active cyclin D-CDK4/6 complex.
Cyclin D-CDK4/6...
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Cyclin E is a
member of the
cyclin family.
Cyclin E
binds to G1
phase Cdk2,
which is
required for the
transition from G1 to S
phase of the cell cycle...
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activity via
multiple mechanisms.
CyclinA-Cdk2
activates Cdc25, an
activator of
cyclin B-Cdk1,
which then
deactivates the
cyclin B-Cdk1 inhibitor, Wee1. This...
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Cyclin D1 is a
protein that in
humans is
encoded by the CCND1 gene. The CCND1 gene
encodes the
cyclin D1 protein. The
human CCND1 gene is
located on the...
- (July 1995). "Mechanism of CDK
activation revealed by the
structure of a
cyclinA-CDK2 complex". Nature. 376 (6538): 313–20. Bibcode:1995Natur.376..313J...
