- In
organic synthesis,
cyanation is the
attachment or
substitution of a
cyanide group on
various substrates. Such
transformations are high-value because...
- can
perform unique transformations on benzene, such as halogenation,
cyanation, trifluoromethylation, and hydroxylation. The
reaction was discovered...
- cyanide.
Lithium cyanide can be used as a
reagent for
organic compound cyanation. RX + LiCN → RCN + LiX J. A. Lely, J. M.
Bijvoet (1942), "The Crystal...
- (toxic) is
largely not encouraged, for this
reason other less
dangerous cyanation reagents are
sought out. In situ
formation of HCN can be
sourced using...
- to the
isomeric aminoiminosuccinonitrile (AISN). It can be
prepared by
cyanation of aminomalonitrile.
Diaminomaleonitrile has been
proposed since the 1960s...
- pesticides, such as
mustard oil.
Illustrative of its
reactivity is its
cyanation to
allyl cyanide (CH2=CHCH2CN).
Being a
reactive alkyl halide, it undergoes...
- water, but is
stable in
aqueous mineral acid.
Synthesis of DDQ
involves cyanation of chloranil. J.
Thiele and F. Günther
first reported a 6-step preparation...
-
Chlorination Clusterification Comproportionation C–C
coupling C–H
activation Cyanation Cyclometalation Decarbonylation Decarboxylation Dehydration Dehalogenation...
- Yan; Yang, Haitao; Cheng,
Jiang (2014). "A copper-mediated
oxidative N-
cyanation reaction".
Chemical Communications. 50 (61): 8412–8415. doi:10.1039/c4cc03439b...
-
exhibits some
biological activity. It is
prepared from
benzaldehyde by
amino cyanation (Strecker synthesis). It can also be
prepared from
glyoxal and by reductive...
