Definition of Costimulator. Meaning of Costimulator. Synonyms of Costimulator

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Definition of Costimulator

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Meaning of Costimulator from wikipedia

- Another costimulatory receptor expressed on T cells is ICOS ( Inducible Costimulator), which interacts with ICOS-L expressed mainly on the APCs. This receptor...
- T-cell costimulator (also called CD278) is an immune checkpoint protein that in humans is encoded by the ICOS (Inducible T-cell COStimulator) gene. The...
- transplantation immunity and tumor immunity. ICOSLG is also a major costimulator in endothelial cell-mediated T cell activation. It has an important physiological...
- CD80 or CD86 (also called B7-1 and B7-2) CD80 and CD86 are known as costimulators for T cell activation. This second signal can be ****isted (or replaced)...
- is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator". Immunity. 16 (3): 479–92. doi:10.1016/S1074-7613(02)00283-2. PMID 11911831...
- aka Butyrophilin subfamily 3 member A1 (BTN3A1) CD278 Inducible T-cell costimulator (ICOS) is an immune checkpoint protein; a CD28-superfamily costimulatory...
- et al. (December 2003). "Analysis of the CTLA-4, CD28, and inducible costimulator (ICOS) genes in autoimmune thyroid disease". Genes and Immunity. 4 (8):...
- concluded that the molecule functioned similarly to CD28 and was a "positive costimulator". They apparently did not pursue CTLA-4 tumor targeting, although BMS...
- Maki RG, London CA, and Abbas AK (1997) Role of interleukin 12 and costimulators in T cell anergy in vivo. Journal of Experimental Medicine 186(7): 1119-28...
- anti-GITR antibodies ICOS: This molecule, short for Inducible T-cell costimulator, and also called CD278, is expressed on activated T cells. Its ligand...