- The
costamere is a structural-functional
component of
striated muscle cells which connects the
sarcomere of the
muscle to the cell
membrane (i.e. the...
-
matrix through the cell membrane. This
complex is
variously known as the
costamere or the dystrophin-****ociated
protein complex (DAPC). Many
muscle proteins...
-
filaments that
slide past each
other when a
muscle contracts or relaxes. The
costamere is a
different component that
connects the
sarcomere to the sarcolemma...
- as the
mitochondria by
intermediate filaments in the cytoskeleton. The
costamere attaches the
sarcomere to the sarcolemma.
Every single organelle and macromolecule...
-
Arrhythmia (irregular heartbeat)
Cardiomyopathy (disease of the
heart muscle)
Costamere Shadrin, I. Y.; Khodabukus, A.; Bursac, N. (June 6, 2016). "Striated muscle...
-
adult striated muscle cells, gamma-actin is
localized to Z-discs and
costamere structures,
which are
responsible for
force transduction and transmission...
- dystrophin-****ociated proteins. It is one of the two
protein complexes that make up the
costamere in
striated muscle cells. The
other complex is the integrin-vinculin-talin...
- of ion
transporters and ion
channels in cardiomyocytes, as well as in
costamere structures.
Mutations in ANK2
cause a dominantly-inherited,
cardiac arrhythmia...
-
skeletal muscle and
smooth muscle cells, and
localizes to Z-disc and
costamere structures.
Mutations in ITGA7 have been ****ociated with
congenital myopathies...
- the TLN1 gene. Talin-1 is
ubiquitously expressed, and is
localized to
costamere structures in
cardiac and
skeletal muscle cells, and to
focal adhesions...
