- Once formed, both C3
convertases will
catalyze the
proteolytic cleavage of C3 into C3a and C3b (hence the name "C3-
convertase"). The
smaller fragment...
-
generate C3
convertase (C4b2b,
historically referred C4b2a),
which cleaves the C3 protein. The C3b
component of the
cleaved C3
binds to C3
convertase (C4b2b)...
-
Proprotein convertases remove those chains and
activate the protein. The
prototypical proprotein convertase is furin.
Proprotein convertases have medical...
- are four
different C5
convertases able to
specifically convert the
protein C5 to C5a and C5b fragments. Two of the
convertases are
physiological complement...
-
because a
section of
peptide chains blocks their activity;
proprotein convertases remove that
section to
activate the enzyme. The PCSK9 gene also contains...
-
belongs to the subtilisin-like
proprotein convertase family. The
members of this
family are
proprotein convertases that
process latent precursor proteins...
-
complex is also
known as a fluid-phase C3-
convertase. This
convertase, the
alternative pathway C3-
convertase,
although only
produced in
small amounts,...
-
endocrine cells versus neurons is
governed by the
expression of
prohormone convertases 1/3, 2, and 5/6". Endocrinology. 149 (4): 1600–8. doi:10.1210/en.2007-0278...
-
Proprotein convertase 1, also
known as
prohormone convertase,
prohormone convertase 3, or
neuroendocrine convertase 1 and
often abbreviated as PC1/3 is...
- is
cleaved by
proteins called convertases in
order to
generate a
mature Nodal. The subtilisin-like
proprotein convertases (SPC)
Furin (Spc1) and PACE4...
