-
different types of
condensin complexes,
known as
condensin I and
condensin II, each of
which is
composed of five
subunits (Figure 2).
Condensins I and II share...
-
identified as the main
components of the scaffold: DNA
topoisomerase IIα,
condensins, and the KIF4A kinesin. When
these proteins are removed, the chromosome...
- grow
loops of DNA or chromatin. In this process, SMC complexes, such as
condensin or cohesin, bind to DNA/chromatin, use ATP-driven
motor activity to reel...
- ten-thousand-fold. The
chromosome scaffold,
which is made of
proteins such as
condensin, TOP2A and KIF4,
plays an
important role in
holding the
chromatin into...
-
order structures.
Chromosome scaffolds are made of
proteins including condensin, type IIA
topoisomerase and
kinesin family member 4 (KIF4). The physical...
- core of the
condensin complexes implicated in
chromosome condensation. SMC2 and SMC4 have the
function of DNA
repair as well.
Condensin I
plays a role...
- that in
humans is
encoded by the SMC4 gene. SMC-4 is a core
subunit of
condensin I and II,
large protein complexes involved in high
order chromosome organization...
- non-SMC
regulatory proteins to form
condensin. In
condensin I, SMC2
complexes with CAP-H, CAP-D2, and CAP-G. In
condensin II, SMC2
complexes with CAP-H2,...
- in
mitosis can be
attributed to the
inactivation of
topoisomerase II,
condensin, or separase.
Meiotic nondisjunction has been well
studied in Saccharomyces...
-
sister DNAs are
segregated into
daughter cells. It has been
shown that
condensin, a
large protein complex that
plays a
central role in
mitotic chromosome...
