-
Religion of
Humanity (from
French Religion de l'Humanité or église positiviste) is a
secular religion created by
Auguste Comte (1798–1857), the founder...
-
encoded by the
COMT gene. Two
isoforms of
COMT are produced: the
soluble short form (S-
COMT) and the
membrane bound long form (MB-
COMT). As the regulation...
-
enzyme catechol-O-methyltransferase (
COMT). When
taken together with
levodopa (L-DOPA) and carbidopa,
entacapone stops COMT from
breaking down levodopa, resulting...
- A catechol-O-methyltransferase
inhibitor (
COMT inhibitor) is a drug that
inhibits the
enzyme catechol-O-methyltransferase. This
enzyme methylates catecholamines...
-
Marshal Cândido
Mariano da
Silva Rondon (5 May 1865 – 19
January 1958) was a
Brazilian military officer most
famous for his
telegraph commission and exploration...
- neurotransmission.
Those involved with
dopamine include DAT, DRD4, DRD5, TAAR1, MAOA,
COMT, and DBH.
Other genes ****ociated with ADHD
include SERT, HTR1B, SNAP25, GRIN2A...
- "Improvement of
prepulse inhibition and
executive function by the
COMT inhibitor tolcapone depends on
COMT Val158Met polymorphism". Neuropsychopharmacology. 33 (13):...
- catechol-O-methyl
transferase (
COMT),
albeit in
reverse order: MAO
catalyzes dopamine to DOPAC, and
COMT catalyzes DOPAC to HVA;
whereas COMT catalyzes dopamine to...
-
require cofactors:
COMT uses Mg2+ as a
cofactor while MAO uses FAD. The
first step of the
catabolic process is
mediated by
either MAO or
COMT which depends...
- catechol-O-methyltransferase (
COMT). It is
peripherally selective and does not
inhibit COMT in the brain. As a
result of its
COMT inhibition,
levodopa remains...
