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Clorgiline (INN), or
clorgyline (BAN), is a
monoamine oxidase inhibitor (MAOI)
structurally related to
pargyline which is
described as an antidepressant...
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amine oxidase,
which is a
class of
enzyme known to
affect carcinogenesis.
Clorgyline, an MAO-A
enzyme inhibitor,
prevents apoptosis in
melanoma cells, in vitro...
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requires combined treatment with both
selegiline and the MAO-A
inhibitor clorgyline. A
close analogue of 2′-CH3-MPTP is 2′-NH2-MPTP, which, in
contrast to...
-
administration of 5-MT in rats were
potentiated by 20-fold by the MAO-A
inhibitor clorgyline and by 5.5-fold by the MAO-B
inhibitor selegiline. Similarly,
levels of...
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inhibitor of type A and B with a
binding affinity somewhat similar to that of
clorgyline and deprenyl. It is a
stronger dopamine releasing agent than nicotine...
-
pargyline is a
benzylamine derivative and is
related to
selegiline and
clorgyline.
Pargyline was
first described in 1960 and was
introduced for medical...
-
oxidase inhibitors (MAOIs). The SSRI
fluoxetine and the MAO-A
inhibitor clorgyline upregulate AANAT indirectly through serotonergic mechanisms and thereby...
- isocarboxazid, and pargyline, MAOA
selective agents like
moclobemide and
clorgyline, and MAOB
selective agents such as
selegiline and rasagiline, as well...
-
Callingham BA (June 1981). "The
acetylenic monoamine oxidase inhibitors clorgyline, deprenyl,
pargyline and J-508:
their properties and applications". J...
- to
decrease DOPAL formation,
however the
irreversible MAO-A
inhibitor clorgyline decreased DOPAL production. The PC12 cell line has been used to get more...
