- In
simple words, the
cistrome refers a
collection of
regulatory elements of a set of genes,
including transcription factor binding sites and
histone modifications...
-
proteins and DNA in vivo. Specifically, it
allows the
identification of the
cistrome, the sum of
binding sites, for DNA-binding
proteins on a genome-wide basis...
-
binding sites of a
specific transcription factor is
referred to as its
cistrome. DNA
binding sites also encomp****es the
targets of
other proteins, like...
-
factors on
promoters or
other DNA
binding sites, and
possibly define cistromes. ChIP also aims to
determine the
specific location in the
genome that...
-
immunoprecipitation followed by deep
sequencing (ChIP-sequencing), and MNase-defined
cistrome-Occupancy
Analysis (MOA-seq),
provide genome-wide
enhancer predictions...
- D968-74. doi:10.1093/nar/gkq997. PMC 3013814. PMID 20972221. https://web.archive.org/web/20110719204256/http://
cistrome.dfci.harvard.edu/CaSNP/ v t e...
- cost-effective fashion,
allowing also for the
characterization of the
cistrome. Previously, DNA
microarray was also used (ChIP-on-chip or ChIP-chip)....
-
understanding of
transcriptional and
epigenetic gene
regulation (MACS,
Cistrome, MDscan, BETA),
CRISPR screens (MAGeCK), and
tumor immunity (TIMER, TIDE...
-
Tsuchida K, Suda H,
Morita M,
Shimizu R,
Yamamoto M (Feb 2016). "Unique
cistrome defined as
CsMBE is
strictly required for Nrf2-sMaf
heterodimer function...
-
Tuxedo pipeline (TopHat, Cufflinks, etc.) ChIP-seq data
analysis with
Cistrome pipeline (MACS, CEAS, etc.) Raw NGS data
processing HMMER 2 and 3 packages...