- Imipenem/
cilastatin, sold
under the
brand name
Primaxin among others, is an
antibiotic useful for the
treatment of a
number of
bacterial infections. It...
-
Cilastatin inhibits the
human enzyme dehydropeptidase.
Dehydropeptidase is an
enzyme found in the
kidney and is
responsible for
degrading the antibiotic...
- Imipenem/
cilastatin/relebactam, sold
under the
brand name Recarbrio(Merck), is a fixed-dose
combination medication used as an antibiotic. In 2019, it was...
-
dehydropeptidase 1 when
administered alone, and is
almost always coadministered with
cilastatin to
prevent this inactivation.
Common adverse drug
reactions are nausea...
- Carbapenems: (meropenem, imipenem/
cilastatin,
doripenem - NOT ertapenem) Meropenem/vaborbactam Imipenem/
cilastatin/relebactam Others: Fluoroquinolones:...
-
combination with
meropenem or imipenem/
cilastatin.
Terizidone is an
alternative Prothionamide is an
alternative Imipenem/
cilastatin is an
alternative For treatment...
- 1984 –
cefotetan 1984 –
temocillin 1985 –
cefpiramide 1985 – imipenem/
cilastatin, the
first carbapenem 1985 –
ofloxacin 1986 –
mupirocin 1986 – aztreonam...
- such as third-generation cephalosporins, fluoroquinolones, and imipenem/
cilastatin are
indicated for
treatment of S.
marcescens skin infections. Surgery...
- intermediate, and thus is co-formulated with the
dehydropeptidase inhibitor cilastatin.
Imipenem is
available in both
intravenous and
intramuscular formulations...
-
novel medicinal compounds. She
worked to
develop the
compound cilastatin sodium.
Cilastatin is an
inhibitor of
renal dehydropeptidase.
Since the antibiotic...
