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Chromoplexy refers to a
class of
complex DNA
rearrangement observed in the
genomes of
cancer cells. This
phenomenon was
first identified in
prostate cancer...
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appreciated that
almost half of EWS and FLI1
fusions are a
result of
chromoplexy.
Evidence of
chromoplectic looping is
enriched in both
metastatic and...
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described by a wide
array of new
terminology (including “chromothripsis,” “
chromoplexy,” “chromoanagenesis,” “chromoanasynthesis,” “chromosome catastrophes...
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related gene, thus
causing the
tumor to be less invasive.
Chromothripsis Chromoplexy Carcinogenesis Nik-Zainal, Serena; Alexandrov,
Ludmil B.; Wedge, David...
- one-off
chromosomal catastrophe model of chromothripsis.
Carcinogenesis Chromoplexy Kataegis Maher CA,
Wilson RK (2012). "Chromothripsis and
Human Disease:...
- of the
Ewing family of tumors.
These translocations can
occur due to
chromoplexy, a
burst of
complex chromosomal rearrangements seen in
cancer cells....
