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Chlorpromazine (CPZ),
marketed under the
brand names Thorazine and
Largactil among others, is an
antipsychotic medication. It is
primarily used to treat...
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clinical use for decades. Perphe****ne is
roughly ten
times as
potent as
chlorpromazine at the dopamine-2 (D2) receptor; thus perphe****ne is
considered a medium-potency...
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Chlorpromazine includes the
following list of
adverse effects (serious
adverse effects appear in bold):
Sedation (cf. "Thorazine shuffle" – a shuffling...
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antipsychotics to come into
medical use were the phenothiazines,
namely chlorpromazine which was
discovered serendipitously.
Another prominent grouping of...
- philosopher. In 1952,
Laborit was
instrumental in the
development of the drug
chlorpromazine,
published his findings, and
convinced three psychiatrists to test it...
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brain tissue volume reduction. First-generation
antipsychotics (e.g.,
chlorpromazine, haloperidol, etc.),
known as
typical antipsychotics, were
first introduced...
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standard effectiveness. It was 13–16% more
effective than ziprasidone,
chlorpromazine, and asenapine,
approximately as
effective as
quetiapine and aripiprazole...
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bioactive and have
widespread use and rich history. The
derivatives chlorpromazine and
promethazine revolutionized the
fields of
psychiatry and allergy...
- schizophrenia,
reserpine and
chlorpromazine had
similar rates of
adverse effects, but that
reserpine was less
effective than
chlorpromazine for
improving a person's...
- diphenhydramine; the same line of
medical chemistry led to the
creation of
chlorpromazine. As of July 2017, it is
marketed under many
brand names worldwide: Allersoothe...
