-
using chemoproteomics, and the
continued improvement of m****
spectrometer sensitivity and
chemical probe technology indicates that
chemoproteomics will...
-
Isoxazole as a
Native Photo-Cross-Linker for
Photoaffinity Labeling and
Chemoproteomics". Angew. Chem. Int. Ed. 61 (47): e202209947. doi:10.1002/anie.202209947...
-
CEllular Thermal Shift ****ay (CETSA®) is a
patented label free
chemoproteomics method that has
enabled measurements of
compound target engagement in intact...
-
chemical compounds against biological targets using biochemical or
chemoproteomics ****ays,
where the
compounds may be from
novel synthetic chemical libraries...
- as
target deconvolution) and validation,
often through the use of
chemoproteomics, to
identify the
mechanisms through which a
phenotypic hit works. Phenotypic...
- [citation needed]
Omics based methods use
omics technologies, such as
chemoproteomics,
reverse genetics and genomics, transcriptomics, and proteomics, to...
-
Photoaffinity labeling is a
chemoproteomics technique used to
attach "labels" to the
active site of a
large molecule,
especially a protein. The "label"...
-
cause psychedelic effects at high doses. The
growth of the
field of
chemoproteomics has
offered a
variety of
strategies to
identify off-targets on a proteome...
- the
compounds through target validation experiments often involving chemoproteomics. More
recently it has
become po****r to
develop a
hypothesis that a...
-
chemical libraries is used to
identify drug
targets (forward
genetics or
chemoproteomics) or to
validate those targets in
experimental models of
disease (reverse...
