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Chemoproteomics (also
known as
chemical proteomics)
entails a
broad array of
techniques used to
identify and
interrogate protein-small
molecule interactions...
-
developed as a
native photo-cross-linker for
photoaffinity labeling and
chemoproteomic studies.
Isoxazoles also form the
basis for a
number of drugs, including...
-
chemical compounds against biological targets using biochemical or
chemoproteomics ****ays,
where the
compounds may be from
novel synthetic chemical libraries...
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CEllular Thermal Shift ****ay (CETSA®) is a
patented label free
chemoproteomics method that has
enabled measurements of
compound target engagement in intact...
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Departments of
Chemistry and
Molecular & Cell Biology. His work
employs chemoproteomic approaches to
develop small molecule therapeutics and
therapeutic modalities...
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their structures and functions. M****
spectrometry techniques are used.
Chemoproteomics: An
array of
techniques used to
study protein-small
molecule interactions...
- [citation needed]
Omics based methods use
omics technologies, such as
chemoproteomics,
reverse genetics and genomics, transcriptomics, and proteomics, to...
- Patrick; Miller,
Aubry K.; Médard, Guillaume; Kuster,
Bernhard (2023). "
Chemoproteomic target deconvolution reveals Histone Deacetylases as
targets of (R)-lipoic...
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Photoaffinity labeling is a
chemoproteomics technique used to
attach "labels" to the
active site of a
large molecule,
especially a protein. The "label"...
- as
target deconvolution) and validation,
often through the use of
chemoproteomics, to
identify the
mechanisms through which a
phenotypic hit works. Phenotypic...
