- are
attracted by
chemokines follow a
signal of
increasing chemokine concentration towards the
source of the
chemokine. Some
chemokines control cells of...
- that
correspond to the 4
distinct subfamilies of
chemokines they bind. The four
subfamilies of
chemokines differ in the
spacing of
structurally important...
-
known CXC
chemokine receptors in mammals,
named CXCR1
through CXCR6. CXCR1 and CXCR2 are
closely related receptors that
recognize CXC
chemokines that possess...
- its
ability to bind
several CC
chemokines (including CCL19, CCL21 and CCL25) and its
structural similarity to
chemokine receptors. However, due to the...
-
diminishes the
ability to bind
chemokines. DARC has also been
linked to
rheumatoid arthritis (RA),
possibly displaying chemokines such as CXCL5 on the surface...
-
cells that is
involved in the
immune system as it acts as a
receptor for
chemokines. In humans, the CCR5 gene that
encodes the CCR5
protein is
located on...
- "Cutting edge:
identification of a
novel chemokine receptor that
binds dendritic cell- and T cell-active
chemokines including ELC, SLC, and TECK". J. Immunol...
-
chemokines have been
implicated in a
number of
inflammatory diseases including atherosclerosis, asthma,
rheumatoid arthritis, and cancer,
chemokine-binding...
- is
located on
human chromosome 4 in a
cluster among several other CXC
chemokines. CXCL10 is
secreted by
several cell
types in
response to IFN-γ. These...
-
monogamous ligand-receptor pair (other
chemokines are promiscuous,
tending to use
several different chemokine receptors).
Recent evidence demonstrates...
