-
Chanoclavine, also
known as chanoclavin-I, is a
tricyclic ergot alkaloid (ergoline)
isolate of
certain fungi. It is
mainly produced by
members of the genus...
-
Chanoclavine II is an
ergoline compound produced by
certain fungi.
Chanoclavine Stauffacher, D.; Tscherter, N. (1964). "Ergot alkaloids. LXIII. Isomers...
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Chanoclavine-I
dehydrogenase (EC 1.1.1.332, easD (gene),
fgaDH (gene)) is an
enzyme with
systematic name
chanoclavine-I:NAD+ oxidoreductase. This enzyme...
- oxidoreductase, EasE, and the catalase, EasC. The
chanoclavine intermediate is then
oxidized to
chanoclavine-l-aldehyde,
catalyzed by the short-chain dehydrogenase/reductase...
-
together with
smaller amounts of d-isolysergic acid
amide (isoergine),
chanoclavine, elymoclavine, and the N-(1-hydroxyethyl)amides of
lysergic and isolysergic...
- 7-OH-DPAT 8-OH-PBZI
Rotigotine UH-232 Ergolines:
Bromocriptine Cabergoline Chanoclavine Dihydroergocryptine Epicriptine Ergocornine Lergotrile Lisuride LSD Pergolide...
- PMID 25036782 “Additionally the
presence of the
ergot alkaloid diastereomers chanoclavine I and II was ****umed in DF (cf. Fig. 6)
together with
traces of lysergic...
- Conversely,
other notable constituents,
including elymoclavine, lysergol, and
chanoclavine,
produced no
psychoactive or
hallucinogenic effects in humans. Ergometrine...
- Chanocalvine-I is then
oxidized to
chanoclavine-I
aldehyde with NAD+
dependent enzyme EasD (FgaDH in A. fumigatus).
Chanoclavine-I
aldehyde is a
branch point...
- example. This
enzyme catalyzes reduction of the C8=C9 double-bond in
chanoclavine I, but EasA
isoforms differ in
whether they
subsequently catalyze reoxidation...
