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Ceramides are a
family of waxy
lipid molecules. A
ceramide is
composed of
sphingosine and a
fatty acid
joined by an
amide bond.
Ceramides are
found in...
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impact on
neural tissue. A
sphingolipid with a
terminal hydroxyl group is a
ceramide.
Other common groups bonded to the
terminal oxygen atom
include phosphocholine...
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Krabbe disease (KD) (also
known as
globoid cell
leukodystrophy or
galactosylceramide lipidosis) is a rare and
often fatal lysosomal storage disease that...
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glycolipid known as
globotriaosylceramide (abbreviated as Gb3, GL-3, or
ceramide trihexoside) to ac****ulate
within the
blood vessels,
other tissues, and...
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solution but, rather,
exist bound to
special carrier proteins in serum.
Ceramide (Cer) can be
generated by the
breakdown of
sphingomyelin (SM) by sphingomyelinases...
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surrounds some
nerve cell axons. It
usually consists of
phosphocholine and
ceramide, or a
phosphoethanolamine head group; therefore,
sphingomyelins can also...
- \rightleftharpoons } ADP +
ceramide 1-phosphate Thus, the two
substrates of this
enzyme are ATP and
ceramide,
whereas its two
products are ADP and
ceramide-1-phosphate...
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Ceramide glucosyltransferase (or
glucosylceramide synthase) is a
glucosyltransferase enzyme involved in the
production of
glucocerebrosides (also called...
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components of
animal muscle and
nerve cell membranes. They
consist of a
ceramide with a
single sugar residue at the 1-hydroxyl moiety. The
sugar residue...
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Ceramide-activated
protein phosphatases (CAPPs) are a
group of
enzymes that are
activated by the
lipid second messenger ceramide.
Known CAPPs include members...
