- chromosome. CepA (Chromosomal
cephalosporinase from
Bacteroides fragilis belonging to
Ambler class A) is an
endogenous cephalosporinase A
described in Bacteroides...
- Beta-lactamases (β-lactamases) are
enzymes (EC 3.5.2.6)
produced by
bacteria that
provide multi-resistance to beta-lactam
antibiotics such as penicillins...
- and amoxicillin/clavulanic acid due to the fact that it
produces a
cephalosporinase enzyme. It is also
resistant to many
other antibiotics,
including penicillin...
-
produce both low-level
inducible cephalosporinases (ceftazidime susceptible) and high-level
constitutive cephalosporinase activity that is
resistant to ceftazidime...
- very
stable in the
presence of β-lactamase (both
penicillinase and
cephalosporinase)
produced by some bacteria, and is a
strong inhibitor of β-lactamases...
- extended-spectrum β-lactamases like PER-1, PER-2, and VEB-1, AmpC
cephalosporinases, carbap****ses like
serine oxacillinases, metallo-b-lactamases, OXA-type...
-
observed to
express beta-lactamases
known as Acinetobacter-derived
cephalosporinases (ADCs),
which are
class C beta-lactamases. In addition, the beta-lactamase...
- β-lactams, it is
highly resistant to
degradation by β-lactamases or
cephalosporinases. In general,
resistance arises due to
mutations in penicillin-binding...
- have the
ability to
become resistant through the
development of
cephalosporinases (enzymes that
hydrolyze cephalosporins and
render them inactive)....
-
While cephalosporinases (a type of beta-lactamase that
inactivates cephalosporins)
confers resistance to
other cephalosporins,
cephalosporinases have not...
