- cell stimulation,
centroblasts are
unable to
differentiate and will
undergo CD95-mediated apoptosis. Morphologically,
centroblasts are
large lymphoid...
- have <5
centroblasts per high-power
field (hpf).
Grade 2:
follicles have 6 to 15
centroblasts per hpf.
Grade 3:
follicles have >15
centroblasts per hpf...
-
cellular division, B
cells of the
germinal center's dark zone are
known as
centroblasts. Once
these B
cells have
stopped proliferating in the dark zone and moved...
-
centroblasts, and
although they are
relatively similar in size,
centrocytes lack
distinct nucleoli and are more
irregularly shaped than
centroblasts....
- cases,
immunoblasts show some
morphologic features of
plasma cells.
Centroblasts are
distinguished from
immunoblasts by
being large lymphoid cells containing...
-
medium size with angulated, elongated, cleaved, or
twisted nuclei. -
Centroblasts are
larger cells containing vesicular nuclei with one to
three basophilic...
- in
which certain lymphocyte types, the B-cell-derived
centrocytes and
centroblasts, form
lymph node follicle-like
structures prin****lly in the duodenum...
- "cleaved" [cleft]
cells (centrocytes)
mixed with
large activated cells (
centroblasts),
usually nodular ("follicular")
growth pattern CD10,
surface Ig About...
-
shows confluent sheets of
large malignant B
lymphocytes that
resemble centroblasts in ~80% of
cases or
immunoblasts in the
remaining ~20% of cases. These...
-
outside its capsule,
follicles present throughout the
entire node,
obvious centroblasts and the
absence or
diminishing mantle zones.
Immunohistochemistry can...
