- The
cation channels of
sperm also
known as
Catsper channels or
CatSper, are ion
channels that are
related to the two-pore
channels and
distantly related...
-
formed by
proteins called CatSper.
These channels are selective,
allowing only
calcium ions to p****. The
opening of
CatSper channels is
responsible for...
- from the ****ulus
cells surrounding the oocyte.
Progesterone binds to the
CatSper receptor on the
sperm membrane and
increases intracellular calcium levels...
-
activation of the
CatSper channel, a
sperm membrane specific calcium channel.
CatSperm can be
activated also by
progesterone and albumine.
CatSper, once activated...
- The
steroid progesterone has been
found to
modulate the
activity of
CatSper (
cation channels of sperm) voltage-gated Ca2+ channels.
Since eggs release...
-
formed by
proteins called CatSper.
These channels are selective,
allowing only
calcium ion to p****. The
opening of
CatSper channels is
responsible for...
-
include the sodium, pot****ium, calcium,
ryanodine receptor, HCN, CNG,
CatSper, and TRP channels. This
large group of ion
channels apparently includes...
-
present in
perimenopausal women.
Progesterone modulates the
activity of
CatSper (
cation channels of sperm) voltage-gated Ca2+ channels.
Since eggs release...
-
mutant mice.
Although CatSper need
additional subunits to
become functional, they are
unrelated to CNG
channels because CatSper lacks a cAMP/cGMP-binding...
- ejaculation.
Inhibitors of
various sperm ion channels/transporters such as
CatSper, sNHE, Slo3, and NKAα4, are in development.
These inhibitors generally...
