-
Apoptotic caspases are
subcategorised as:
Initiator Caspases (
Caspase 2,
Caspase 8,
Caspase 9,
Caspase 10)
Executioner Caspases (
Caspase 3,
Caspase 6 and...
- acid
protease (
caspase) family.
Sequential activation of
caspases plays a
central role in the execution-phase of cell apoptosis.
Caspases exist as inactive...
- of
caspases:
initiator caspases (
caspases 2, 8, 9, 10, 11, and 12) and
effector caspases (
caspases 3, 6, and 7). The
activation of
initiator caspases requires...
-
express caspase-9 at low levels.
Active caspase-9
works as an
initiating caspase by cleaving, thus
activating downstream executioner caspases, initiating...
-
proteases called caspases. It is an
inflammatory caspase,
along with
caspase 1,
caspase 4 and the
murine caspase 4
homolog caspase 11, and has a role...
-
called caspases. The
function of
caspase 4 is not
fully known, but it is
believed to be an
inflammatory caspase,
along with
caspase 1,
caspase 5 (and...
- acid
protease (
caspase) family.
Sequential activation of
caspases plays a
central role in the execution-phase of cell apoptosis.
Caspases exist as inactive...
-
Caspases are
classified into two
fundamental groups:
initiator caspases,
including caspase-8 and
caspase-9, and
executioner caspases, such as
caspase-3...
- Wang Y, Gao W, Ding J, Li P, Hu L, Shao F (October 2014). "Inflammatory
caspases are
innate immune receptors for
intracellular LPS". Nature. 514 (7521):...
-
Caspase 12 is a
protein that in
humans is
encoded by the CASP12 gene. The
protein belongs to a
family of
enzymes called caspases which cleave their substrates...
