- In
organic chemistry, a
hemiaminal (also
carbinolamine) is a
functional group or type of
chemical compound that has a
hydroxyl group and an
amine attached...
- an
aldehyde reacting with a
secondary amine to form an
enamine via a
carbinolamine intermediate is
shown below: Even
though enamines are more nucleophilic...
-
oxygen atom to
create a
carbinolamine. In the case of a
primary amine, a
water molecule can be
eliminated from the
carbinolamine intermediate to
yield an...
- "O-Debenzylation of a Pyrrolo[2,1-c][1,4]benzodiazepine in the
Presence of a
Carbinolamine Functionality:
Synthesis of DC-81". Synthesis. 1990: 81–84. doi:10.1055/s-1990-26795...
- Pterin-4-alpha-
carbinolamine dehydratase is an
enzyme that in
humans is
encoded by the PCBD1 gene. This gene
encodes pterin-4 alpha-
carbinolamine dehydratase...
- Pterin-4 alpha-
carbinolamine dehydratase deficiency (PCDD) is one of the
known forms of
tetrahydrobiopterin deficiency. This
condition is ****ociated with...
-
cofactor 5,6,7,8-tetrahydrobiopterin (BH4) into tetrahydrobiopterin-4a-
carbinolamine (4a-BH4).
Under physiological conditions, 4a-BH4 is
dehydrated to...
-
followed by
stabilizing interactions at the
active site. Finally, key
lysine residues and the
carbinolamine intermediate are shown.
Based on PDB 1JCL...
-
transfer of a
proton from
nitrogen to
oxygen to a
stable hemiaminal or
carbinolamine. With
primary amines,
water is lost in an
elimination reaction to an...
-
amine on THF
attacks the free
formaldehyde intermediate to make the
carbinolamine intermediate. In the
second case, the
nucleophilic amines on THF attack...
