Definition of Camptothecin. Meaning of Camptothecin. Synonyms of Camptothecin

- Camptothecin (CPT) is a topoisomerase inhibitor. It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for...
- confer resistance to camptothecin. Indenosioquinolines and indolocarbazoles also lack the lactone ring present in camptothecin, making them more chemically...
- included on the World Health Organization's List of Essential Medicines. Camptothecin (Fig. 7), originally derived from the tree Camptotheca a****inata, targets...
- Organization's List of Essential Medicines. It is made from the natural compound camptothecin which is found in the Chinese ornamental tree Camptotheca a****inata....
- antineoplastic drug. It is the active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor) but has 1000 times more activity than...
- is a synthetic, water-soluble analog of the natural chemical compound camptothecin. It is used in the form of its hydrochloride salt to treat ovarian cancer...
- and stems of C. a****inata contain the alkaloid camptothecin. Several chemical derivatives of camptothecin are under investigation for or used as drugs for...
- name Zofran/ Emiston in BD Some cancer chemotherapy drugs, including camptothecin derivatives Mirtazapine, a noradrenergic and specific serotonergic antidepressant...
- Exatecan is a drug which is a structural analog of camptothecin with antineoplastic activity. A derivative is used in Trastuzumab deruxtecan. Abou-Alfa...
- showed modest activity in SCLC patients refractory to both etoposide- and camptothecin-based chemotherapy. The newer agent lurbinectedin is active in relapsed...