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Calnexin (CNX) is a 67kDa
integral protein (that
appears variously as a 90kDa, 80kDa, or 75kDa band on
western blotting depending on the
source of the...
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loading complex consisting of TAP, tapasin, calreticulin,
calnexin, and Erp57 (PDIA3).
Calnexin acts to
stabilize the
class I MHC α
chains prior to β2m...
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Rhodes Scholar (class of 1966). He is best
known for the
discovery of
calnexin,
endosomal signalling and
organellar proteomics.
Bergeron was born in Belleville...
- chaperone,
calnexin,
performs the same
service for
soluble proteins as does calreticulin,
however it is a membrane-bound protein. Both proteins,
calnexin and...
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protein disulfide isomerase (PDI), ERp29, the Hsp70
family member BiP/Grp78,
calnexin, calreticulin, and the
peptidylprolyl isomerase family. Only
properly folded...
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involved in
hormone and drug
action Affect folding of
certain proteins Calnexin,
calreticulin Regulation of
development Notch and its analogs, key proteins...
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called glycan processing. In this mechanism, the lectin-type
chaperones calnexin/calreticulin (CNX/CRT)
provide immature glycoproteins the
opportunity to...
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which therapies might be beneficial. Lp(a) has been
shown to
interact with
calnexin, fibronectin, and
fibrinogen beta chain.
Medicine portal Lipoprotein –...
-
ligand for the
lectin molecules calreticulin (CRT;
soluble in ER lumen) and
calnexin (CNX;
membrane bound).
Favoured by the
highly oxidizing environment of...
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involved in the ER
quality control system are UGGT, the ER
lectin chaperones (
calnexin and calreticulin), and
glucosidase II. UGGT
first recognizes the incompletely...