- The
calicheamicins are a
class of
enediyne antitumor antibiotics derived from the
bacterium Micromonospora echinospora, with
calicheamicin γ1
being the...
-
antitumor antibiotic calicheamicin (N-acetyl-γ-
calicheamicin)
payload via a
bifunctional linker (4-(4-acetylphenoxy)butanoic acid).
Calicheamicin (the payload)...
-
against CD22 (inotuzumab),
linked to a
cytotoxic agent from the
class of
calicheamicins called ozogamicin. The US Food and Drug
Administration (FDA) considers...
-
during a
search for new
anticancer products produced by microorganisms.
Calicheamicin was one of the
first such
products identified and was
originally found...
-
river Styx (modern-day
Mavroneri in Arcadia, Greece) that
contained calicheamicin, a
dangerous compound produced by bacteria.
Several natural causes (diseases)...
- G.A. Ellestad; D.
Kahne (1992). "Cleavage
behavior of
calicheamicin gamma 1 and
calicheamicin T". Proc Natl Acad Sci USA. 89 (10): 4608–12. Bibcode:1992PNAS...
-
covalently attached to the
cytotoxic antitumor antibiotic calicheamicin (N-acetyl-γ-
calicheamicin) via a
bifunctional linker (4-(4-acetylphenoxy)butanoic...
-
Peloponnesian peninsula. Its
waters contain a
significant amount of
Calicheamicin, a
dangerous compound produced by bacteria.
Stanford University scientists...
- tumors. The
calicheamicins are a sub-family of
enediynes that were
isolated from
Micromonospora echinospora calichensis. All
calicheamicin family members...
- gentamicin, mutamicin, netilmicin, retymicin, sisomicin, verdamicin,
calicheamicin, and the
recently found turbinmicin.
Potent new
antifungal drugs discovered...