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Calcineurin (CaN) is a
calcium and
calmodulin dependent serine/threonine
protein phosphatase (also
known as
protein phosphatase 3, and calcium-dependent...
-
administration in the
combination with
other immunosuppressants, for example,
calcineurin inhibitors, cytostatics, and corticosteroids. The most
frequent combination...
- used to
treat dry eye
syndrome in cats and dogs.
Tacrolimus inhibits calcineurin,
which is
involved in the
production of interleukin-2, a
molecule that...
-
Pimecrolimus is an
immunosuppressant drug of the
calcineurin inhibitor class used in the
treatment of
atopic dermatitis (eczema). It is
available as a...
- Ciclosporin, also
spelled cyclosporine and cyclosporin, is a
calcineurin inhibitor, used as an
immunosuppressant medication. It is
taken orally or intravenously...
- The
calcineurin-like
phosphoesterases are a
family of
enzymes related to
calcineurin. It
includes a
diverse range of phosphoesterases,
including protein...
-
corticosteroid therapy is the most
commonly used treatment, and
topical calcineurin inhibitors have also been used successfully. At the
first stages of the...
- Voclosporin, sold
under the
brand name Lupkynis, is a
calcineurin inhibitor used as an
immunosuppressant medication for the
treatment of
lupus nephritis...
-
advantage sirolimus has over
calcineurin inhibitors is its low
toxicity toward kidneys.
Transplant patients maintained on
calcineurin inhibitors long-term tend...
- CRZ1,
short for
Calcineurin-Responsive Zinc
Finger 1, is a
transcription factor that
regulates calcineurin dependent-genes in
Candida albicans. The cytoplasmic...