-
Colchicine is a
medication used to
prevent and
treat gout, to
treat familial Mediterranean fever and Behçet's disease, and to
reduce the risk of myocardial...
-
Standard agents involve non-steroidal anti-inflammatory
drugs (NSAIDs),
colchicine and glucocorticoids. On the
other hand,
drugs for
maintenance therapy...
- with
nonsteroidal anti-inflammatory
drugs (NSAIDs), glucocorticoids, or
colchicine improves symptoms. Once the
acute attack subsides,
levels of uric acid...
-
cytoskeleton (microtubules) that is failing, as
suggested by the
efficacy of
colchicine. It is not
conclusively known what
exactly sets off the
attacks or why...
- are
similar to
colchicine and bind to the
colchicine binding site on β-tubulin so
development of
novel agents acting with
colchicine binding site (which...
- post-pericardiotomy syndrome,
colchicine seems to
provide an
effective and safe way to
treat pericarditis by
reducing inflammation.
Colchicine is a
natural product...
- Azithromycin,
should not be
taken with
colchicine as it may lead to
colchicine toxicity.
Symptoms of
colchicine toxicity include gastrointestinal upset...
- bulb-like
corms of C.
autumnale contain colchicine, a
useful drug with a
narrow therapeutic index.
Colchicine is
approved in many
countries for the treatment...
- most
cases is with
NSAIDs and
possibly the anti-inflammatory
medication colchicine.
Steroids may be used if
these are not appropriate.
Symptoms usually improve...
- with
colchicine as the
result of
inhibition of CYP3A4
metabolism and P-glycoprotein transport.
Combining these two
drugs may lead to
fatal colchicine toxicity...
