-
CIITA is a
human gene
which encodes a
protein called the
class II,
major histocompatibility complex, transactivator.
Mutations in this gene are responsible...
-
class II
expression is
closely regulated in APCs by
CIITA,
which is the MHC
class II transactivator.
CIITA is
solely expressed on
professional APCs; however...
- type of N-terminal domain: NLRA (A for
acidic transactivating domain):
CIITA NLRB (B for BIRs): NAIP NLRC (C for CARD): NOD1, NOD2, NLRC3, NLRC4, NLRC5...
- HGNC:1976 O60543 3053
CIDEB HGNC:1977 Q9UHD4 3054
CIDEC HGNC:24229 Q96AQ7 3055
CIITA HGNC:7067 P33076 3056 CILK1 HGNC:21219 Q9UPZ9 3057 CILP HGNC:1980 O75339...
- A
class II gene is a type of gene that
codes for a protein.
class II
genes are
transcribed by RNAP II [citation needed].
class II
genes have a promoter...
-
proteins that
contain it: NAIP (NLP
family apoptosis inhibitor protein),
CIITA (that is, C2TA or MHC
class II
transcription activator), HET-E (incompatibility...
- 24% with Komo. The
language is also
called Opo-****a, Opo, Opuo, Cita,
Ciita, ****a (along with Dana), Shiita, Ansita, Kina, and Kwina. The self-name...
- Zinc finger, X-linked,
duplicated family member C (ZXDC) is a
human CIITA-binding
protein involved in the
activation of
major histocompatibility complex...
-
other proteins the most
important are: the MHC
class II
transactivator (
CIITA), IPAF, BIRC1 etc. The
ligands are
currently known for NOD1 and NOD2. NOD1...
-
prevent NK
cells attacks due to
deletion of HLA.
Deletion of the B2M and
CIITA genes using the CRISPR/Cas9
system has been
reported to
suppress the expression...
