-
Cyclic ADP-ribose,
frequently abbreviated as
cADPR, is a
cyclic adenine nucleotide (like cAMP) with two
phosphate groups present on 5' OH of the adenosine...
-
enzyme poly ADP
ribose polymerase. ADPR is
created from
cyclic ADP-ribose (
cADPR) by the CD38
enzyme using nicotinamide adenine dinucleotide (NAD+) as a...
- to
synthesize the calcium-releasing
second messengers cyclic ADP-ribose (
cADPR) and
nicotinic acid
adenine dinucleotide phosphate (NAADP). CD38 is most...
- the
chemical reaction NAD+ + H2O ⇌ {\displaystyle \rightleftharpoons }
cADPR + H2O +
nicotinamide ⇌ {\displaystyle \rightleftharpoons } ADP-ribose +...
- "Biochemistry, biology, and
pharmacology of
cyclic adenosine diphosphoribose (
cADPR)". Curr. Med. Chem. 11 (7): 847–55. doi:10.2174/0929867043455602. PMID 15078169...
-
forms pyrophosphate esters, e.g.
tetraethyl pyrophosphate, ADP, dADP, ADPR,
cADPR, CDP, dCDP, GDP, dGDP, UDP, dTDP, MEcPP, HMBPP, DMAPP, IPP, GPP, FPP, GGPP...
- QB, Wang QS,
Collier ML,
Fleischer S, et al. (March 2004). "FKBP12.6 and
cADPR regulation of Ca2+
release in
smooth muscle cells".
American Journal of...
- or
extracellular NADase,
whereas type II CD38
contains an
intracellular cADPR. CD38
consumes NAD,
which can
produce second messengers that help regulate...
-
Second messengers IP3
NAADP cADPR Intracellular channels IP3
receptor Ryanodine receptor Calcium-induced
calcium release Intracellular pumps SERCA ATP2A1...
-
Second messengers IP3
NAADP cADPR Intracellular channels IP3
receptor Ryanodine receptor Calcium-induced
calcium release Intracellular pumps SERCA ATP2A1...
