-
formation of the
transcriptional complex. An
example is the E-box (sequence
CACGTG),
which binds transcription factors in the
basic helix-loop-helix (bHLH)...
- ATF/CREB
Basic zipper 5'-TGACGTCA-3'
Dimer c-Myc
Basic helix-loop-helix 5'-
CACGTG-3'
Dimer Oct-1 Helix-turn-helix 5'-ATGCAAAT-3'
Monomer NF-1
Novel 5'-TTGGC****XXGCCAA-3'...
-
DNNYGCTKAVTCAGCRNNH MAX ENSG00000125952 bHLH
Known motif – High-throughput in
vitro [507]
CACGTG MAZ ENSG00000103495 C2H2 ZF
Known motif – High-throughput in
vitro [508]...
- (where N can be any nucleotide), with a
palindromic canonical sequence of
CACGTG, is
recognized and
bound by
transcription factors to
initiate gene transcription...
- to a
consensus sequence called an E-box, CANNTG. The
canonical E-box is
CACGTG (palindromic),
however some bHLH
transcription factors,
notably those of...
- Bst2UI, BthEI, MvaI,
SspAI SnoI
Streptomyces novocastria 5'
GTGCAC 3'
CACGTG 5' ---G TGCAC--- 3' 3' ---CACGT G--- 5' Alw44I, ApaLI, VneI SolI Streptoverticillium...
- PMID 2162525.
Kafri T,
Hershko A,
Razin A (June 1993). "Probing CpG
methylation at
CACGTG with
BbrPI restriction enzyme".
Nucleic Acids Res. 21 (12): 2950. doi:10...
- and wounding. The CHS
promoter contains a G-box
motif with a
sequence of
CACGTG. This has been
shown to play a role in
response to light.
Other light sensitive...
-
proteins show high
binding affinity for the ACGT motifs,
which include CACGTG (G box),
GACGTC (C box),
TACGTA (A box),
AACGTT (T box), and a GCN4 motif...
-
enhancer upstream of the gene. This
enhancer sequence contained an E-box (
CACGTG),
which was
determined to be
necessary for high-level per transcription...
