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Bryostatins are a
group of
macrolide lactones from (bacterial
symbionts of) the
marine organism Bugula neritina that were
first collected and provided...
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since been used in the
synthesis of
several products,
particularly the
bryostatins. Evans–Tishchenko
reaction Saksena, Anil; Mangiaracina,
Pietro (1983)...
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Endobugula sertula,
produces the
bryostatins, a
group of
around twenty bioactive natural products. The
bryostatins are
under investigation for their...
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called bryostatins can be
extracted from the
marine bryozoan Bugula neritina. In 2001
pharmaceutical company GPC
Biotech licensed bryostatin 1 from Arizona...
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Bugula neritina attracted interest as a
source of
cytotoxic chemicals,
bryostatins,
under clinical investigation as anti-cancer agents. It was
first collected...
- fish meal),
pharmaceuticals (e.g. fish oil,
krill oil,
cytarabine and
bryostatin) and
various industrial chemicals (e.g.
chitin and bioplastics, formerly...
- (CSTI-500) – serotonin, norepinephrine, and
dopamine reuptake inhibitor Bryostatin 1 (MW-904) –
protein kinase C (PKC)
stimulant BTRX-246040 (LY-2940094)...
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Other naturally occurring PKCIs are
miyabenol C, myricitrin, gossypol.
Bryostatin 1 can act as a PKC inhibitor; It was
investigated for cancer. Darovasertib...
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highly chemoselective oxyfunctionalization of the C-9
position of
potent bryostatin analogues".
Organic Letters. 7 (1): 79–82. doi:10.1021/ol047859w. PMID 15624982...
- "Identifying
bryostatins and
potential precursors from the
bryozoan 'Bugula neritina'",
Natural Product Research 19.5 (2005) 467–1 Halford, B. "The
Bryostatins' Tale"...
