-
Bryostatins are a
group of
macrolide lactones from (bacterial
symbionts of) the
marine organism Bugula neritina that were
first collected and provided...
-
called bryostatins can be
extracted from the
marine bryozoan Bugula neritina. In 2001
pharmaceutical company GPC
Biotech licensed bryostatin 1 from Arizona...
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Other naturally occurring PKCIs are
miyabenol C, myricitrin, gossypol.
Bryostatin 1 can act as a PKC inhibitor; It was
investigated for cancer. Darovasertib...
- than was
previously achieved. For example,
total syntheses of roxaticin,
bryostatin and
cryptocaryol were
accomplished via
double Krische allylation of 1...
- fish meal),
pharmaceuticals (e.g. fish oil,
krill oil,
cytarabine and
bryostatin) and
various industrial chemicals (e.g.
chitin and bioplastics, formerly...
-
since been used in the
synthesis of
several products,
particularly the
bryostatins. Evans–Tishchenko
reaction Saksena, Anil; Mangiaracina,
Pietro (1983)...
-
discovery that
Bryostatin-1 can be used to
treat latent HIV
infection and
formed the
basis for
clinical trials on the use of
Bryostatin as a
latent infection-reversing...
- cancer, anti-inflammatory use and pain. One
class of
these agents are
bryostatin-like compounds,
under investigation as anti-cancer therapy.[citation needed]...
- 1998). "Reversible
phosphorylation of Bcl2
following interleukin 3 or
bryostatin 1 is
mediated by
direct interaction with
protein phosphatase 2A". The...
- (IW-2143) – α7
nicotinic acetylcholine receptor negative allosteric modulator Bryostatin 1 (MW-904) –
protein kinase C (PKC)
stimulant BTRX-246040 (LY-2940094)...
