-
alkylating agent. The
pyruvate transporter system can be used to
deliver bromopyruvate inside trypanosomal cells. Once intracellular, the
primary target of...
-
including SB-204990, 2-deoxy-D-glucose (2DG), 3-
bromopyruvate (3-BrPA,
bromopyruvic acid, or
bromopyruvate), 3-bromo-2-oxopropionate-1-propyl
ester (3-BrOP)...
- 4-diyl dibenzoate, PC10907289 (3).
Cyclization with
Ethyl bromopyruvate [70-23-5] (4) led to 2-(2,3,5-Tri-O-benzoyl-beta-D-ribofuranosyl)-4-thiazolecarboxylic...
- of the
acidic ammonium hydrogen with the
dicarbonyl group of
ethyl bromopyruvate in a 5-membered
transition state.
Franz Feist (1902). "Studien in der...
- articles,
according to Web of Science. The most
cited was
Meloche HP. "
Bromopyruvate inactivation of 2-keto-3-deoxy-phosphogluconic aldolase. I. Kinetic...
-
inhibition of
phosphoenolpyruvate carboxylase from
maize leaves by
bromopyruvate".
Archives of
Biochemistry and Biophysics. 245 (1): 179–86. doi:10...
- of an anti-cancer drug
currently undergoing clinical trials called 3-
bromopyruvate in
breast cancer cells. Most
cases of
alveolar soft part
sarcoma show...
-
Peppelenbosch MP, et al. (June 2019). "Targeting
Tyrosine Phosphatases by 3-
Bromopyruvate Overcomes Hyperactivation of
Platelets from
Gastrointestinal Cancer...
- have
already been identified,
including itaconate,
itaconic anhydride,
bromopyruvate, nitropropionate, oxalate, and malate,
these are non-specific and would...
