- had two
bromodomains, and one
protein had 6
bromodomains. Preparation,
biochemical analysis, and
structure determination of the
bromodomain containing...
-
targeting BET
bromodomains. BET
inhibitors have been
described that are able to
discriminate between the
first and
second bromodomains of BET proteins...
- BRD3, and BRDT. BRD4,
similar to
other BET
family members,
contains two
bromodomains that
recognize acetylated lysine residues. BRD4 also has an extended...
-
contain HAT
domains that are
approximately 500
residues long and
contain bromodomains as well as
three cysteine-histidine rich
domains that help with protein...
- protein–protein
interaction domains, such as the acetyllysine-binding
bromodomain[citation needed].
Histone acetyltransferases can also
acetylate non-histone...
- of the
Bromodomain and Extra-Terminal
motif (BET)
protein family. Like
other BET
family members it
contains two
tandem homologous bromodomains and an...
-
Bromodomain-containing
protein 2 is a
protein that in
humans is
encoded by the BRD2 gene. BRD2 is part of the
Bromodomain and Extra-Terminal
motif (BET)...
- P. E. (2014). "1,2,4triazolo4,3-aphthalazines:
Inhibitors of
diverse bromodomains".
Journal of
Medicinal Chemistry. 57 (2): 462–76. doi:10.1021/jm401568s...
- WB,
Fedorov O, et al. (December 2010). "Selective
inhibition of BET
bromodomains". Nature. 468 (7327): 1067–73. Bibcode:2010Natur.468.1067F. doi:10.1038/nature09504...
- transduction, apoptosis, and gene regulation. This
protein contains 2
bromodomains and 8 WD repeats, and the
function of this
protein is not known. This...
